Finally got around to trying
Strange Rider in a Chalice deck and it's surprisingly fun.
Dinosaur Nest is the most unusual inclusion among the 16 relics I'm running in the deck. It generates tokens that can be Chalice'd and if the first Valley is already reached, later Dinosaur Nests act as another potential wincon. Naturally, you can also cheese wins by playing multiple on the first few turns.
The other relics are self-explanatory:
Crystalline Chalice because duh.
Stormhalt Knife as removal and a great card in particular against aggro. Finally,
Stormhalt Plating is what you use to end games and the inscribe is very relevant as well.
When the new campaign drops, I'm definitely going to experiment with Celestial Discovery over Honor of Claws.