Sandscar Exodia

Update: I finally made this meme combo deck somewhat functional. It's still horrible, but now it can occasionally win a game.

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The Combo:
Azurite Prixis, Porcelain Mask, Shepherd's Horn, Means to an End, and Cheering Section.

Prixis + Cheering Section summons a unit -> Mask gives the unit overwhelm -> Horn gives you health for summoning the unit -> Memes discards cards equal to the gained health -> Cheering Section summons a unit because you discarded cards -> etc.
This repeats until you run out of cards or board space. If the latter, sac your totemites with Cheering Section to do it again. After the second loop, you will almost certainly be out of cards triggering Memes and (hopefully) burning your opponent to death.

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Math: (since you will probably be a blocker most of the time)
# of cards discarded (not counting the ones that start the loop) = T * 3 * S * M * (1 + C) + T * C * A
- T = # of totemites you have room for (or 12 - the number of non-totemites you have)
- S = # of Shepherd's Horns
- M = # of Means to an End (also affects your final damage)
- C = # of Cheering Sections
- A = # of Azurite Prixis

Example: Assuming you have the minimum required relics and 4 non-totemite units in play, you will discard 56 cards over the two loops.
{ 8 * 3 * 1 * 1 * (1 + 1) + 8 * 1 * 1 = 8 * 3 * 2 + 8 = 56 }

This is basically the standard worst case of the combo going off and it's usually still enough to deck you by the time it goes off. Multiples of any of the non-mask relics will greatly increase the amount of cards you self-mill.